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BKMS-react is an integrated and non-redundant biochemical reaction database containing known enzyme-catalyzed and spontaneous reactions. Biochemical reactions collected from BRENDA, KEGG, MetaCyc and SABIO-RK were matched and integrated by aligning substrates and products.
 

:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
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  • EC Number
  • Reaction
  • Pathways
  • Reaction IDs
  • Stoichiometry Check
  • Missing Substrate
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  • Commentary
  • Remark
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check  
Commentary
curcumin synthase
(4-coumaroyl)acetyl-CoA + feruloyl-CoA + H2O = demethoxycurcumin + CO2 + 2 CoA
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: curcuminoid synthase (CURS)
: A polyketide synthase from the plant TAX-136217 (turmeric). Three isoforms exist, G-11801, G-11802 and G-11803. While CURS1 and CURS2 prefer feruloyl-CoA as a starter substrate (cf. EC 2.3.1.ag, curcumin synthase), CURS3 can accept 4-coumaroyl-CoA equally well [19622354].
demethoxycurcumin synthase
(4-coumaroyl)acetyl-CoA + feruloyl-CoA + H2O = demethoxycurcumin + CO2 + 2 CoA
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: curcuminoid synthase (CURS)
: A polyketide synthase from the plant TAX-136217 (turmeric). Three isoforms exist, G-11801, G-11802 and G-11803. While CURS1 and CURS2 prefer feruloyl-CoA as a starter substrate (cf. EC 2.3.1.ag, curcumin synthase), CURS3 can accept 4-coumaroyl-CoA equally well [19622354].