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BKMS-react is an integrated and non-redundant biochemical reaction database containing known enzyme-catalyzed and spontaneous reactions. Biochemical reactions collected from BRENDA, KEGG, MetaCyc and SABIO-RK were matched and integrated by aligning substrates and products.
 

:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
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  • EC Number
  • Reaction
  • Pathways
  • Reaction IDs
  • Stoichiometry Check
  • Missing Substrate
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  • Commentary
  • Remark
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check  
Commentary
chalcone isomerase
A chalcone = a flavanone
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: Chalcone is 2'-hydroxylated (see [CPD:C09321], R02898) general reaction (see R02446, R06556, R07990 and R07995)
chalcone isomerase
4,2',4'-trihydroxychalcone = (2S)-4',7-dihydroxyflavanone
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: chalcone isomerase
: Functional and structural studies have indicated that chalcone isomerase, catalyzing the first step towards isoflavonoids, accelerates the stereochemically defined intramolecular cyclization of chalcones into biologically active (2S)-flavanones by selectively binding an ionized chalcone in a conformation conducive to ring closure in a diffusion-controlled reaction.
Muconate cycloisomerase
cis,cis-Muconate = 5-Oxo-2,5-dihydrofuran-2-acetate
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Carboxy-cis,cis-muconate cyclase
cis,cis-Muconate = 5-Oxo-2,5-dihydrofuran-2-acetate
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isoleucine-tRNA ligase
Ile-tRNAIle + cysteine = tRNAIle + isoleucylcysteine
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chalcone isomerase
4,2',4',6'-Tetrahydroxychalcone = 5,7,4'-Trihydroxyflavanone
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