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BKMS-react is an integrated and non-redundant biochemical reaction database containing known enzyme-catalyzed and spontaneous reactions. Biochemical reactions collected from BRENDA, KEGG, MetaCyc and SABIO-RK were matched and integrated by aligning substrates and products.
 

:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
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  • EC Number
  • Reaction
  • Pathways
  • Reaction IDs
  • Stoichiometry Check
  • Missing Substrate
  • Missing Product
  • Commentary
  • Remark
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check  
Commentary
presqualene diphosphate synthase
2 (2E,6E)-farnesyl diphosphate = diphosphate + presqualene diphosphate
-
: first step of two-step reaction (R06223, R00702+R02872) first step of two-step reaction (R07652, R00702+R09793)
: This reaction is catalyzed by the presqualene diphosphate synthase (SSL-1) enzyme of the green alga TAX-869301. However, it is also a partial reaction catalyzed by two different enzymes - |FRAME:RXN-13162 "EC 2.5.1.21, squalene synthase"| and EC 2.5.1.96, 4,4'-diapophytoene synthase. The product, CPD-465, is only fromed by the presqualene diphosphate synthase of TAX-38881. In the other two cases, it is never released from the enzyme and is directly converted to the final product, squalene and 4,4'-diapophytoene, respectively.
squalene synthase
2 (2E,6E)-farnesyl diphosphate = diphosphate + presqualene diphosphate
-
: first step of two-step reaction (R06223, R00702+R02872) first step of two-step reaction (R07652, R00702+R09793)
: This reaction is catalyzed by the presqualene diphosphate synthase (SSL-1) enzyme of the green alga TAX-869301. However, it is also a partial reaction catalyzed by two different enzymes - |FRAME:RXN-13162 "EC 2.5.1.21, squalene synthase"| and EC 2.5.1.96, 4,4'-diapophytoene synthase. The product, CPD-465, is only fromed by the presqualene diphosphate synthase of TAX-38881. In the other two cases, it is never released from the enzyme and is directly converted to the final product, squalene and 4,4'-diapophytoene, respectively.
4,4'-diapophytoene synthase
2 (2E,6E)-farnesyl diphosphate = diphosphate + presqualene diphosphate
-
: first step of two-step reaction (R06223, R00702+R02872) first step of two-step reaction (R07652, R00702+R09793)
: This reaction is catalyzed by the presqualene diphosphate synthase (SSL-1) enzyme of the green alga TAX-869301. However, it is also a partial reaction catalyzed by two different enzymes - |FRAME:RXN-13162 "EC 2.5.1.21, squalene synthase"| and EC 2.5.1.96, 4,4'-diapophytoene synthase. The product, CPD-465, is only fromed by the presqualene diphosphate synthase of TAX-38881. In the other two cases, it is never released from the enzyme and is directly converted to the final product, squalene and 4,4'-diapophytoene, respectively.