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BKMS-react is an integrated and non-redundant biochemical reaction database containing known enzyme-catalyzed and spontaneous reactions. Biochemical reactions collected from BRENDA, KEGG, MetaCyc and SABIO-RK were matched and integrated by aligning substrates and products.

:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
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  • EC Number
  • Reaction
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  • Stoichiometry Check
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EC Number
Reaction IDs
Stoichiometry Check  
inositol-polyphosphate multikinase
ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate
: This enzyme also phosphorylates Ins(1,4,5)P(3) to Ins(1,3,4,5)P(4), Ins(1,3,4,5)P(4) to Ins(1,3,4,5,6)P(5), and Ins(1,3,4,5,6)P(4) to Ins(PP)P(4), isomer unknown. The enzyme from the plant Arabidopsis thaliana can also phosphorylate Ins(1,3,4,6)P(4) and Ins(1,2,3,4,6)P(5) at the D-5-position to produce 1,3,4,5,6-pentakisphosphate and inositol hexakisphosphate (InsP(6)), respectively. Yeast produce InsP(6) from Ins(1,4,5)P(3) by the actions of this enzyme and EC This enzyme also phosphorylates Ins(1,4,5)P3 to Ins(1,3,4,5)P4, Ins(1,4,5,6)P4 to Ins(1,3,4,5,6)P5, Ins(1,3,4,5)P4 to Ins(1,3,4,5,6)P5, and Ins(1,3,4,5,6)P4 to Ins(PP)P4, isomer unknown.