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BRENDA KEGG MetaCyc

lysine metabolism (BRENDA)

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EC Number Recommended Name Reaction BRENDA Pathway Name KEGG Pathway Name MetaCyc Pathway Name Reaction ID BRENDA Reaction ID KEGG Reaction ID MetaCyc Reaction ID SABIO-RK
show all sequences1.5.1.1 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H] L-pipecolate + NADP+ = 1-piperideine-2-carboxylate + NADPH + H+ lysine metabolism Lysine degradation,
Tropane, piperidine and pyridine alkaloid biosynthesis,
Metabolic pathways
L-pipecolate biosynthesis,
L-lysine degradation II (L-pipecolate pathway),
L-lysine degradation V
BR36897 show the reaction diagram R02203 show the reaction diagram RXN-8166 show the reaction diagram 2175
show all sequences1.5.1.21 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH) L-pipecolate + NADP+ = 1-piperideine-2-carboxylate + NADPH + H+ lysine metabolism Lysine degradation,
Tropane, piperidine and pyridine alkaloid biosynthesis,
Metabolic pathways
L-pipecolate biosynthesis,
L-lysine degradation II (L-pipecolate pathway),
L-lysine degradation V
BR36897 show the reaction diagram R02203 show the reaction diagram RXN-8166 show the reaction diagram 2175
show all sequences1.5.1.49 1-pyrroline-2-carboxylate reductase [NAD(P)H] L-pipecolate + NADP+ = 1-piperideine-2-carboxylate + NADPH + H+ lysine metabolism Lysine degradation,
Tropane, piperidine and pyridine alkaloid biosynthesis,
Metabolic pathways
L-pipecolate biosynthesis,
L-lysine degradation II (L-pipecolate pathway),
L-lysine degradation V
BR36897 show the reaction diagram R02203 show the reaction diagram RXN-8166 show the reaction diagram 2175
show all sequences3.5.1.30 5-aminopentanamidase 5-aminopentanamide + H2O = 5-aminopentanoate + NH3 lysine metabolism Lysine degradation L-lysine degradation IV BR19244 show the reaction diagram R02273 show the reaction diagram 5-AMINOPENTANAMIDASE-RXN show the reaction diagram  
show all sequences1.13.12.2 lysine 2-monooxygenase L-lysine + O2 = 5-aminopentanamide + CO2 + H2O lysine metabolism Lysine degradation L-lysine degradation IV BR40522 show the reaction diagram R00449 show the reaction diagram LYSINE-2-MONOOXYGENASE-RXN show the reaction diagram  
show all sequences5.4.3.2 lysine 2,3-aminomutase L-lysine = (3S)-3,6-diaminohexanoate lysine metabolism Lysine degradation L-lysine fermentation to acetate and butanoate BR26 show the reaction diagram R00461 show the reaction diagram LYSINE-23-AMINOMUTASE-RXN show the reaction diagram  
show all sequences1.5.1.7 saccharopine dehydrogenase (NAD+, L-lysine-forming) N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O = L-lysine + 2-oxoglutarate + NADH + H+ lysine metabolism Lysine biosynthesis,
Lysine degradation,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of antibiotics,
Biosynthesis of amino acids
L-lysine biosynthesis IV BR37179 show the reaction diagram R00715 show the reaction diagram 1.5.1.7-RXN show the reaction diagram 1087
show all sequences2.3.1.247 3-keto-5-aminohexanoate cleavage enzyme (5S)-5-amino-3-oxohexanoate + acetyl-CoA = L-3-aminobutanoyl-CoA + acetoacetate lysine metabolism Lysine degradation L-lysine fermentation to acetate and butanoate BR51399 show the reaction diagram R10564 show the reaction diagram R125-RXN show the reaction diagram  
show all sequences4.1.1.20 diaminopimelate decarboxylase meso-2,6-Diaminoheptanedioate = L-lysine + CO2 lysine metabolism Lysine biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Biosynthesis of amino acids
L-lysine biosynthesis I,
L-lysine biosynthesis VI,
L-lysine biosynthesis III,
L-lysine biosynthesis II
BR281 show the reaction diagram,
BS390203 show the reaction diagram
R00451 show the reaction diagram DIAMINOPIMDECARB-RXN show the reaction diagram  
show all sequences2.6.1.39 2-aminoadipate transaminase L-2-aminoadipate + 2-oxoglutarate = 2-oxoadipate + L-glutamate lysine metabolism Lysine biosynthesis,
Lysine degradation,
Metabolic pathways,
Biosynthesis of antibiotics,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
L-lysine degradation II (L-pipecolate pathway),
L-lysine biosynthesis IV,
L-lysine degradation V,
L-lysine biosynthesis V,
L-lysine degradation XI (mammalian)
BR47689 show the reaction diagram R01939 show the reaction diagram 2-AMINOADIPATE-AMINOTRANSFERASE-RXN show the reaction diagram 1992
show all sequences2.6.1.36 L-lysine 6-transaminase L-lysine + 2-oxoglutarate = (S)-2-amino-6-oxohexanoate + L-glutamate lysine metabolism Metabolic pathways L-lysine degradation VI BR47436 show the reaction diagram,
BS354059 show the reaction diagram
R00457 show the reaction diagram L-LYSINE-AMINOTRANSFERASE-RXN show the reaction diagram 894
show all sequences6.3.2.43 [lysine-biosynthesis-protein LysW]-L-2-aminoadipate ligase L-2-Aminoadipate + alpha-Aminoadipate carrier protein LysW + ATP <=> LysW-gamma-L-alpha-aminoadipate + ADP + Orthophosphate lysine metabolism Lysine biosynthesis,
Metabolic pathways,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
    R09775 show the reaction diagram    
show all sequences6.3.2.43 [lysine-biosynthesis-protein LysW]-L-2-aminoadipate ligase ATP + [lysine-biosynthesis-protein LysW]-C-terminal-L-glutamate + L-2-aminoadipate = ADP + phosphate + [lysine-biosynthesis-protein LysW]-C-terminal-gamma-(L-2-aminoadip-2-yl)-L-glutamate lysine metabolism     BR50906 show the reaction diagram      
show all sequences1.5.1.10 saccharopine dehydrogenase (NADP+, L-glutamate-forming) N6-(L-1,3-dicarboxypropyl)-L-lysine + NADP+ + H2O = L-glutamate + (S)-2-amino-6-oxohexanoate + NADPH + H+ lysine metabolism Lysine biosynthesis,
Lysine degradation,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of antibiotics,
Biosynthesis of amino acids
L-lysine biosynthesis IV BR40355 show the reaction diagram,
BS287686 show the reaction diagram
R02315 show the reaction diagram RXN3O-127 show the reaction diagram  
show all sequences1.17.1.8 4-hydroxy-tetrahydrodipicolinate reductase 2,3-dihydrodipicolinate + NADPH = 2,3,4,5-tetrahydrodipicolinate + NADP+ lysine metabolism     BS258380 show the reaction diagram      
show all sequences4.3.3.7 4-hydroxy-tetrahydrodipicolinate synthase L-aspartate-4-semialdehyde + pyruvate = dihydrodipicolinate + H2O lysine metabolism     BS18740 show the reaction diagram,
BS415661 show the reaction diagram
    12754,
2256
SPONTANEOUS   (S)-2-aminoadipate 6-semialdehyde = (S)-2,3,4,5-tetrahydropiperidine-2-carboxylate + H2O lysine metabolism Tropane, piperidine and pyridine alkaloid biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites
L-lysine degradation VI,
L-lysine degradation IX,
L-lysine degradation VIII
BS413149 show the reaction diagram R02317 show the reaction diagram RXN-8173 show the reaction diagram  
show all sequences1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase (S)-2-aminoadipate 6-semialdehyde = (S)-2,3,4,5-tetrahydropiperidine-2-carboxylate + H2O lysine metabolism Tropane, piperidine and pyridine alkaloid biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites
L-lysine degradation VI,
L-lysine degradation IX,
L-lysine degradation VIII
BS413149 show the reaction diagram R02317 show the reaction diagram RXN-8173 show the reaction diagram  
show all sequences1.4.1.18 lysine 6-dehydrogenase (S)-2-aminoadipate 6-semialdehyde = (S)-2,3,4,5-tetrahydropiperidine-2-carboxylate + H2O lysine metabolism Tropane, piperidine and pyridine alkaloid biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites
L-lysine degradation VI,
L-lysine degradation IX,
L-lysine degradation VIII
BS413149 show the reaction diagram R02317 show the reaction diagram RXN-8173 show the reaction diagram  
2.6.1.M4   [2-aminoadipate carrier protein]-C-terminal-L-glutamyl-gamma-L-lysine + 2-oxoglutarate = [2-aminoadipate carrier protein]-C-terminal-L-glutamyl-gamma-L-2-aminoadipate semialdehyde + L-glutamate lysine metabolism   L-lysine biosynthesis V     RXN-5184 show the reaction diagram  
show all sequences5.1.1.7 diaminopimelate epimerase LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate lysine metabolism Lysine biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Biosynthesis of amino acids
L-lysine biosynthesis I,
L-lysine biosynthesis VI,
L-lysine biosynthesis II
BR175 show the reaction diagram R02735 show the reaction diagram DIAMINOPIMEPIM-RXN show the reaction diagram  
show all sequences1.1.1.286 isocitrate-homoisocitrate dehydrogenase (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate + NAD+ = 2-oxoadipate + CO2 + NADH + H+ lysine metabolism Lysine biosynthesis,
Metabolic pathways,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
L-lysine biosynthesis IV,
coenzyme B biosynthesis,
L-lysine biosynthesis V
BR48021 show the reaction diagram R01934 show the reaction diagram RXN-7970 show the reaction diagram  
show all sequences1.1.1.87 homoisocitrate dehydrogenase (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate + NAD+ = 2-oxoadipate + CO2 + NADH + H+ lysine metabolism Lysine biosynthesis,
Metabolic pathways,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
L-lysine biosynthesis IV,
coenzyme B biosynthesis,
L-lysine biosynthesis V
BR48021 show the reaction diagram R01934 show the reaction diagram RXN-7970 show the reaction diagram  
show all sequences1.5.1.8 saccharopine dehydrogenase (NADP+, L-lysine-forming) N6-(L-1,3-dicarboxypropyl)-L-lysine + NADP+ + H2O = L-lysine + 2-oxoglutarate + NADPH + H+ lysine metabolism Lysine degradation,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of antibiotics
L-lysine degradation XI (mammalian) BR36904 show the reaction diagram R00716 show the reaction diagram 1.5.1.8-RXN show the reaction diagram 1088
show all sequences1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + NAD+ + 2 H2O <=> L-2-Aminoadipate + NADH + H+ lysine metabolism   L-lysine degradation II (L-pipecolate pathway),
L-lysine degradation V,
L-lysine degradation VI
BS189205 show the reaction diagram R11231 show the reaction diagram RXN-10855_WOP show the reaction diagram,
RXN-8162 show the reaction diagram
 
    (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + NAD+ + 2 H2O <=> L-2-Aminoadipate + NADH + H+ lysine metabolism   L-lysine degradation II (L-pipecolate pathway),
L-lysine degradation V,
L-lysine degradation VI
BS189205 show the reaction diagram R11231 show the reaction diagram RXN-10855_WOP show the reaction diagram,
RXN-8162 show the reaction diagram
 
4.2.1.-   (R)-2-hydroxybutane-1,2,4-tricarboxylate = (Z)-but-1-ene-1,2,4-tricarboxylate + H2O lysine metabolism Lysine biosynthesis,
Metabolic pathways,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
L-lysine biosynthesis IV,
coenzyme B biosynthesis,
L-lysine biosynthesis V
BR49014 show the reaction diagram,
BS1972 show the reaction diagram
R03444 show the reaction diagram RXN3O-1983 show the reaction diagram 3238
show all sequences4.2.1.114 methanogen homoaconitase (R)-2-hydroxybutane-1,2,4-tricarboxylate = (Z)-but-1-ene-1,2,4-tricarboxylate + H2O lysine metabolism Lysine biosynthesis,
Metabolic pathways,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
L-lysine biosynthesis IV,
coenzyme B biosynthesis,
L-lysine biosynthesis V
BR49014 show the reaction diagram,
BS1972 show the reaction diagram
R03444 show the reaction diagram RXN3O-1983 show the reaction diagram 3238
show all sequences4.2.1.36 homoaconitate hydratase (R)-2-hydroxybutane-1,2,4-tricarboxylate = (Z)-but-1-ene-1,2,4-tricarboxylate + H2O lysine metabolism Lysine biosynthesis,
Metabolic pathways,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
L-lysine biosynthesis IV,
coenzyme B biosynthesis,
L-lysine biosynthesis V
BR49014 show the reaction diagram,
BS1972 show the reaction diagram
R03444 show the reaction diagram RXN3O-1983 show the reaction diagram 3238
    (R)-2-hydroxybutane-1,2,4-tricarboxylate = (Z)-but-1-ene-1,2,4-tricarboxylate + H2O lysine metabolism Lysine biosynthesis,
Metabolic pathways,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
L-lysine biosynthesis IV,
coenzyme B biosynthesis,
L-lysine biosynthesis V
BR49014 show the reaction diagram,
BS1972 show the reaction diagram
R03444 show the reaction diagram RXN3O-1983 show the reaction diagram 3238
show all sequences1.5.1.9 saccharopine dehydrogenase (NAD+, L-glutamate-forming) N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O = L-glutamate + (S)-2-amino-6-oxohexanoate + NADH + H+ lysine metabolism Lysine degradation,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of antibiotics
L-lysine degradation XI (mammalian) BR37178 show the reaction diagram,
BS261177 show the reaction diagram
R02313 show the reaction diagram 1.5.1.9-RXN show the reaction diagram 2273
show all sequences2.6.1.17 succinyldiaminopimelate transaminase N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-L-2-amino-6-oxoheptanedioate + L-glutamate lysine metabolism Lysine biosynthesis,
Metabolic pathways,
Microbial metabolism in diverse environments,
Biosynthesis of amino acids
L-lysine biosynthesis I BR47417 show the reaction diagram R04475 show the reaction diagram SUCCINYLDIAMINOPIMTRANS-RXN show the reaction diagram  
    N6-Acetyl-LL-2,6-diaminoheptanedioate + 2-Oxoglutarate <=> N-Acetyl-L-2-amino-6-oxopimelate + L-Glutamate lysine metabolism Lysine biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of amino acids
L-lysine biosynthesis II   R04467 show the reaction diagram RXN-4822 show the reaction diagram  
2.6.1.-   N6-Acetyl-LL-2,6-diaminoheptanedioate + 2-Oxoglutarate <=> N-Acetyl-L-2-amino-6-oxopimelate + L-Glutamate lysine metabolism Lysine biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of amino acids
L-lysine biosynthesis II   R04467 show the reaction diagram RXN-4822 show the reaction diagram  
    L-lysine = 1-piperideine 6-carboxylate lysine metabolism   apicidin biosynthesis,
apicidin F biosynthesis
    RXN-16669 show the reaction diagram  
    L-Lysine <=> L-Pipecolate lysine metabolism       R00459 show the reaction diagram    
    (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate <=> L-Pipecolate lysine metabolism Tropane, piperidine and pyridine alkaloid biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites
    R08414 show the reaction diagram    
    L-Pipecolate <=> 1-Indolizidinone lysine metabolism Tropane, piperidine and pyridine alkaloid biosynthesis,
Biosynthesis of secondary metabolites
    R08415 show the reaction diagram    
3.5.99.-   L-2-Amino-6-oxoheptanedioate <=> 2,3,4,5-Tetrahydrodipicolinate + H2O lysine metabolism Lysine biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of amino acids
L-lysine biosynthesis III   R04336 show the reaction diagram RXN-4821 show the reaction diagram  
SPONTANEOUS   L-2-Amino-6-oxoheptanedioate <=> 2,3,4,5-Tetrahydrodipicolinate + H2O lysine metabolism Lysine biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of amino acids
L-lysine biosynthesis III   R04336 show the reaction diagram RXN-4821 show the reaction diagram  
show all sequences1.17.1.8 4-hydroxy-tetrahydrodipicolinate reductase (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NADP+ + H2O = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NADPH + H+ lysine metabolism Monobactam biosynthesis,
Lysine biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Biosynthesis of amino acids
L-lysine biosynthesis I,
L-lysine biosynthesis VI,
L-lysine biosynthesis III,
L-lysine biosynthesis II
BR36807 show the reaction diagram R04199 show the reaction diagram RXN-14014 show the reaction diagram  
show all sequences2.6.1.48 5-aminovalerate transaminase 5-aminopentanoate + 2-oxoglutarate = 5-oxopentanoate + L-glutamate lysine metabolism Lysine degradation L-lysine degradation X,
L-lysine degradation IV,
L-lysine degradation III
BR47695 show the reaction diagram R02274 show the reaction diagram VAGL-RXN show the reaction diagram  
show all sequences5.1.1.5 lysine racemase L-lysine = D-lysine lysine metabolism Lysine degradation L-lysine degradation V BR173 show the reaction diagram R00460 show the reaction diagram LYSINE-RACEMASE-RXN show the reaction diagram  
show all sequences5.1.1.9 arginine racemase L-lysine = D-lysine lysine metabolism Lysine degradation L-lysine degradation V BR173 show the reaction diagram R00460 show the reaction diagram LYSINE-RACEMASE-RXN show the reaction diagram  
show all sequences3.5.1.47 N-acetyldiaminopimelate deacetylase N-acetyl-LL-2,6-diaminoheptanedioate + H2O = acetate + LL-2,6-diaminoheptanedioate lysine metabolism Lysine biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of amino acids
L-lysine biosynthesis II BR19248 show the reaction diagram,
BS116335 show the reaction diagram
R02733 show the reaction diagram N-ACETYLDIAMINOPIMELATE-DEACETYLASE-RXN show the reaction diagram  
show all sequences4.1.1.50 adenosylmethionine decarboxylase L-lysine = cadaverine + CO2 lysine metabolism Lysine degradation,
Tropane, piperidine and pyridine alkaloid biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites
L-lysine degradation X,
L-lysine degradation I,
bisucaberin biosynthesis,
desferrioxamine E biosynthesis,
desferrioxamine B biosynthesis,
lupanine biosynthesis,
aminopropylcadaverine biosynthesis
BR6435 show the reaction diagram R00462 show the reaction diagram LYSDECARBOX-RXN show the reaction diagram 899
show all sequences4.1.1.B12 lysine/ornithine carboxy-lyase L-lysine = cadaverine + CO2 lysine metabolism Lysine degradation,
Tropane, piperidine and pyridine alkaloid biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites
L-lysine degradation X,
L-lysine degradation I,
bisucaberin biosynthesis,
desferrioxamine E biosynthesis,
desferrioxamine B biosynthesis,
lupanine biosynthesis,
aminopropylcadaverine biosynthesis
BR6435 show the reaction diagram R00462 show the reaction diagram LYSDECARBOX-RXN show the reaction diagram 899
show all sequences4.1.1.17 ornithine decarboxylase L-lysine = cadaverine + CO2 lysine metabolism Lysine degradation,
Tropane, piperidine and pyridine alkaloid biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites
L-lysine degradation X,
L-lysine degradation I,
bisucaberin biosynthesis,
desferrioxamine E biosynthesis,
desferrioxamine B biosynthesis,
lupanine biosynthesis,
aminopropylcadaverine biosynthesis
BR6435 show the reaction diagram R00462 show the reaction diagram LYSDECARBOX-RXN show the reaction diagram 899
show all sequences4.1.1.18 lysine decarboxylase L-lysine = cadaverine + CO2 lysine metabolism Lysine degradation,
Tropane, piperidine and pyridine alkaloid biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites
L-lysine degradation X,
L-lysine degradation I,
bisucaberin biosynthesis,
desferrioxamine E biosynthesis,
desferrioxamine B biosynthesis,
lupanine biosynthesis,
aminopropylcadaverine biosynthesis
BR6435 show the reaction diagram R00462 show the reaction diagram LYSDECARBOX-RXN show the reaction diagram 899
show all sequences4.1.1.19 arginine decarboxylase L-lysine = cadaverine + CO2 lysine metabolism Lysine degradation,
Tropane, piperidine and pyridine alkaloid biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites
L-lysine degradation X,
L-lysine degradation I,
bisucaberin biosynthesis,
desferrioxamine E biosynthesis,
desferrioxamine B biosynthesis,
lupanine biosynthesis,
aminopropylcadaverine biosynthesis
BR6435 show the reaction diagram R00462 show the reaction diagram LYSDECARBOX-RXN show the reaction diagram 899
show all sequences1.4.1.16 diaminopimelate dehydrogenase meso-2,6-diaminoheptanedioate + H2O + NADP+ = L-2-amino-6-oxoheptanedioate + NH3 + NADPH + H+ lysine metabolism Lysine biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of amino acids
L-lysine biosynthesis III BR36864 show the reaction diagram R02755 show the reaction diagram DIAMINOPIMELATE-DEHYDROGENASE-RXN show the reaction diagram  
show all sequences1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase (S)-2-amino-6-oxohexanoate + NADP+ + H2O = L-2-aminoadipate + NADPH + H+ lysine metabolism Lysine degradation,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of antibiotics
L-lysine degradation XI (mammalian) BR29399 show the reaction diagram R03103 show the reaction diagram 1.2.1.31-RXN show the reaction diagram  
2.6.1.-   6-N-acetyl-L-lysine + 2-oxoglutarate = 6-(N-acetylamino)-2-oxohexanoate + L-glutamate lysine metabolism Lysine degradation L-lysine degradation III BS354063 show the reaction diagram R04029 show the reaction diagram ACETCAPR-RXN show the reaction diagram  
show all sequences2.6.1.36 L-lysine 6-transaminase 6-N-acetyl-L-lysine + 2-oxoglutarate = 6-(N-acetylamino)-2-oxohexanoate + L-glutamate lysine metabolism Lysine degradation L-lysine degradation III BS354063 show the reaction diagram R04029 show the reaction diagram ACETCAPR-RXN show the reaction diagram  
show all sequences2.6.1.65 N6-acetyl-beta-lysine transaminase 6-N-acetyl-L-lysine + 2-oxoglutarate = 6-(N-acetylamino)-2-oxohexanoate + L-glutamate lysine metabolism Lysine degradation L-lysine degradation III BS354063 show the reaction diagram R04029 show the reaction diagram ACETCAPR-RXN show the reaction diagram  
show all sequences4.3.3.7 4-hydroxy-tetrahydrodipicolinate synthase pyruvate + L-aspartate-4-semialdehyde = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O lysine metabolism Monobactam biosynthesis,
Lysine biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
Biosynthesis of amino acids
L-lysine biosynthesis I,
L-lysine biosynthesis VI,
L-lysine biosynthesis III,
L-lysine biosynthesis II
BR3399 show the reaction diagram R10147 show the reaction diagram DIHYDRODIPICSYN-RXN show the reaction diagram  
3.5.1.-   5-acetamidopentanoate + H2O = acetate + 5-aminopentanoate lysine metabolism Lysine degradation L-lysine degradation III BS189973 show the reaction diagram R02276 show the reaction diagram AMVAL-RXN show the reaction diagram  
show all sequences3.5.1.63 4-acetamidobutyrate deacetylase 5-acetamidopentanoate + H2O = acetate + 5-aminopentanoate lysine metabolism Lysine degradation L-lysine degradation III BS189973 show the reaction diagram R02276 show the reaction diagram AMVAL-RXN show the reaction diagram  
1.2.1.M4   [2-aminoadipate carrier protein]-C-terminal-L-glutamyl-gamma-L-2-aminoadipate 6-phosphate + NADPH + H+ = [2-aminoadipate carrier protein]-C-terminal-L-glutamyl-gamma-L-2-aminoadipate semialdehyde + NADP+ + phosphate lysine metabolism   L-lysine biosynthesis V     RXN-5183 show the reaction diagram  
show all sequences5.4.3.3 lysine 5,6-aminomutase (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate lysine metabolism Lysine degradation L-lysine fermentation to acetate and butanoate BR27 show the reaction diagram R03275 show the reaction diagram BETA-LYSINE-56-AMINOMUTASE-RXN show the reaction diagram  
show all sequences5.4.3.4 D-lysine 5,6-aminomutase (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate lysine metabolism Lysine degradation L-lysine fermentation to acetate and butanoate BR27 show the reaction diagram R03275 show the reaction diagram BETA-LYSINE-56-AMINOMUTASE-RXN show the reaction diagram  
show all sequences1.2.1.20 glutarate-semialdehyde dehydrogenase 5-oxopentanoate + NAD+ + H2O = glutarate + NADH + H+ lysine metabolism Lysine degradation L-lysine degradation III BR29392 show the reaction diagram R02401 show the reaction diagram GLUTARATE-SEMIALDEHYDE-DEHYDROGENASE-RXN show the reaction diagram 2340
show all sequences1.2.1.88 L-glutamate gamma-semialdehyde dehydrogenase 5-oxopentanoate + NAD+ + H2O = glutarate + NADH + H+ lysine metabolism Lysine degradation L-lysine degradation III BR29392 show the reaction diagram R02401 show the reaction diagram GLUTARATE-SEMIALDEHYDE-DEHYDROGENASE-RXN show the reaction diagram 2340
show all sequences6.1.1.6 lysine-tRNA ligase ATP + L-lysine + tRNALys = AMP + diphosphate + L-lysyl-tRNALys lysine metabolism     BR57 show the reaction diagram      
1.1.1.-   5-Acetamidopentanoate + NADH + H+ + CO2 <=> 6-Acetamido-2-oxohexanoate + NAD+ + H2O lysine metabolism Lysine degradation L-lysine degradation III   R04142 show the reaction diagram KETAMID-RXN show the reaction diagram  
1.2.4.-   5-Acetamidopentanoate + NADH + H+ + CO2 <=> 6-Acetamido-2-oxohexanoate + NAD+ + H2O lysine metabolism Lysine degradation L-lysine degradation III   R04142 show the reaction diagram KETAMID-RXN show the reaction diagram  
show all sequences1.4.1.18 lysine 6-dehydrogenase L-lysine + NAD+ + H2O = (S)-2-amino-6-oxohexanoate + NADH + H+ + NH3 lysine metabolism Tropane, piperidine and pyridine alkaloid biosynthesis,
Metabolic pathways
L-lysine degradation VIII BR36866 show the reaction diagram,
BS371013 show the reaction diagram
R00446 show the reaction diagram RXN-8808 show the reaction diagram  
    L-lysine + NAD+ + H2O = (S)-2-amino-6-oxohexanoate + NADH + H+ + NH3 lysine metabolism Tropane, piperidine and pyridine alkaloid biosynthesis,
Metabolic pathways
L-lysine degradation VIII BR36866 show the reaction diagram,
BS371013 show the reaction diagram
R00446 show the reaction diagram RXN-8808 show the reaction diagram  
show all sequences4.2.1.114 methanogen homoaconitase (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate = (Z)-but-1-ene-1,2,4-tricarboxylate + H2O lysine metabolism Lysine biosynthesis,
Metabolic pathways,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
L-lysine biosynthesis IV,
coenzyme B biosynthesis,
L-lysine biosynthesis V
BR416 show the reaction diagram R04371 show the reaction diagram HOMOACONITATE-HYDRATASE-RXN show the reaction diagram 4067
show all sequences4.2.1.36 homoaconitate hydratase (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate = (Z)-but-1-ene-1,2,4-tricarboxylate + H2O lysine metabolism Lysine biosynthesis,
Metabolic pathways,
Microbial metabolism in diverse environments,
Biosynthesis of antibiotics,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
L-lysine biosynthesis IV,
coenzyme B biosynthesis,
L-lysine biosynthesis V
BR416 show the reaction diagram R04371 show the reaction diagram HOMOACONITATE-HYDRATASE-RXN show the reaction diagram 4067
show all sequences3.5.1.18 succinyl-diaminopimelate desuccinylase N-succinyl-LL-2,6-diaminoheptanedioate + H2O = succinate + LL-2,6-diaminoheptanedioate lysine metabolism Lysine biosynthesis,
Metabolic pathways,
Microbial metabolism in diverse environments,
Biosynthesis of amino acids
L-lysine biosynthesis I BR26098 show the reaction diagram,
BS414993 show the reaction diagram
R02734 show the reaction diagram SUCCDIAMINOPIMDESUCC-RXN show the reaction diagram 2621
show all sequences2.6.1.83 LL-diaminopimelate aminotransferase LL-2,6-diaminoheptanedioate + 2-oxoglutarate = (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + L-glutamate + H2O lysine metabolism Lysine biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Biosynthesis of antibiotics,
Biosynthesis of amino acids
L-lysine biosynthesis VI BR48748 show the reaction diagram,
BS424856 show the reaction diagram
R07613 show the reaction diagram RXN-7737 show the reaction diagram 12290