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:= amino acid sequences

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Results 1 - 10 of 17

EC Number

Reaction

Pathways

Reaction IDs

Stoichiometry Check

Missing Substrate

Missing Product

Commentary

Remark

4.1.3.1

isocitrate lyase

(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = succinate + pyruvate

: propionate fermentation

: Propanoate metabolism

: 2-methylcitrate cycle II,
2-methylcitrate cycle I

: BR390

, BS417300

: R00409

: METHYLISOCITRATE-LYASE-RXN

: 866

natural substrates

4.1.3.30

Methylisocitrate lyase

(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = succinate + pyruvate

: propionate fermentation

: Propanoate metabolism

: 2-methylcitrate cycle II,
2-methylcitrate cycle I

: BR390

, BS417300

: R00409

: METHYLISOCITRATE-LYASE-RXN

: 866

natural substrates

2.3.3.16

citrate synthase (unknown stereospecificity)

propanoyl-CoA + H2O + oxaloacetate = (2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate + CoA

: propionate fermentation

: Propanoate metabolism

: 2-methylcitrate cycle II,
2-methylcitrate cycle I

: BR44127

, BS321797

, BS407305

: R00931

: 2-METHYLCITRATE-SYNTHASE-RXN

: 1249

natural substrates

2.3.3.5

2-methylcitrate synthase

propanoyl-CoA + H2O + oxaloacetate = (2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate + CoA

: propionate fermentation

: Propanoate metabolism

: 2-methylcitrate cycle II,
2-methylcitrate cycle I

: BR44127

, BS321797

, BS407305

: R00931

: 2-METHYLCITRATE-SYNTHASE-RXN

: 1249

natural substrates

4.2.1.117

2-methylcitrate dehydratase (2-methyl-trans-aconitate forming)

(2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate = (Z)-but-2-ene-1,2,3-tricarboxylate + H2O

: propionate fermentation

: Propanoate metabolism

: 2-methylcitrate cycle I

: BR456

, BS2113

, BS444085

: R04424

: 2-METHYLCITRATE-DEHYDRATASE-RXN

: 4111

natural substrates

4.2.1.79

2-methylcitrate dehydratase

(2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate = (Z)-but-2-ene-1,2,3-tricarboxylate + H2O

: propionate fermentation

: Propanoate metabolism

: 2-methylcitrate cycle I

: BR456

, BS2113

, BS444085

: R04424

: 2-METHYLCITRATE-DEHYDRATASE-RXN

: 4111

natural substrates

4.2.1.3

aconitate hydratase

(2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylate = (Z)-but-2-ene-1,2,3-tricarboxylate + H2O

: propionate fermentation

: Propanoate metabolism

: 2-methylcitrate cycle II,
2-methylcitrate cycle I

: BR471

, BS18710

: R04425

: 4.2.1.99-RXN

: 4112

: reversible reaction Ref. 1: Biosci. Biotech. Biochem., 59 (11), 2013-2017, 1995

natural substrates

4.2.1.99

2-methylisocitrate dehydratase

(2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylate = (Z)-but-2-ene-1,2,3-tricarboxylate + H2O

: propionate fermentation

: Propanoate metabolism

: 2-methylcitrate cycle II,
2-methylcitrate cycle I

: BR471

, BS18710

: R04425

: 4.2.1.99-RXN

: 4112

: reversible reaction Ref. 1: Biosci. Biotech. Biochem., 59 (11), 2013-2017, 1995

natural substrates

4.2.1.117

2-methylcitrate dehydratase (2-methyl-trans-aconitate forming)

(2S,3S)-2-methylcitrate = 2-methyl-trans-aconitate + H2O

: Propanoate metabolism

: 2-methylcitrate cycle II

: BR49126

: R11263

: RXN-8979

natural substrates

6.2.1.1

acetate-CoA ligase

ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA

: propanol degradation,
alanine metabolism,
isoleucine metabolism

: Metabolic pathways

: 2-methylcitrate cycle II,
L-isoleucine biosynthesis IV,
2-methylcitrate cycle I,
beta-alanine biosynthesis II

: BR68

: R00925

: PROPIONATE--COA-LIGASE-RXN

: 1245

: two-step reaction (see R01354+R00926)

natural substrates

Results 1 - 10 of 17